【摘要】 目的探讨活体心肌氢质子磁共振波谱(proton magnetic resonance spectroscopy,1H-MRS)扫描的可行性。方法采用1.5T磁共振扫描仪对100名志愿者进行心肌1H-MRS扫描,分析所得谱线。结果 100名志愿者均完成检查,水峰位于4.7ppm,显示率为100%,胆碱(choline,Cho)峰位于3.2ppm,显示率为86%,肌酸(creatine,Cr)峰位于3.0ppm,显示率为90%,甘油三酯(triglyceride,TG)峰位于0.9～1.6ppm,显示率为98%。共86例可见上述所有波峰,以代谢物的峰高与水峰峰高的比值表示代谢物含量,根据86例谱线计算出Cho含量为1.94%,Cr含量为1.95%,TG含量为9.41%。结论 1H-MRS可以检测活体心肌相关代谢产物。更多还原

【Abstract】 Objective To investigate the feasibility of proton magnetic resonance spectroscopy(1H-MRS) of the myocardium in vivo.Methods A total of 100 volunteers were examined with 1H-MRS scan using a 1.5T MR scanner,and the magnetic resonance spectra were analyzed.Results All the volunteers completed the examinations,and the spectral peaks were identified with the chemical shifts of water(4.7 ppm),choline(3.2 ppm),creatine(3.0 ppm),and triglyceride(0.9-1.6 ppm),whose presentation ratios were 100%,86%,90%,and 98%,respectively.In 86 cases the spectra showed all the chemical shifts.The myocardial metabolite contents were expressed as the ratio of metabolites to water(%),and the contents of choline,creatine,and triglyceride were 1.94%,1.95%,and 9.41%,respectively.Conclusion 1H-MRS can be used in detecting the metabolic products of myocardium in vivo.更多还原