【摘要】 目的分析与评价部分脾动脉栓塞术预防食管胃底静脉曲张再出血的临床疗效。方法 62例近期发生食管胃底静脉曲张破裂出血患者,采用Seldinger技术进行部分脾动脉栓塞术,观察其外周血细胞、肝功、凝血酶原时间、门静脉内径及内镜下曲张静脉的变化等,术后随访12个月。结果所有患者经过部分脾动脉栓塞术治疗5d后,外周血白细胞、血小板明显增加(P<0.05),凝血酶原时间缩短(P<0.05)。4周后门静脉管径缩小,血流量减小(P<0.05)。复查胃镜食管胃底静脉曲张不同程度缓解,11例(17.74%)在随访中再次发生上消化道出血。结论部分脾动脉栓塞术对食管静脉曲张再出血有明显预防作用。更多还原

【Abstract】 Objective To evaluate the effect of partial splenic embolization (PSE) in prevention of gastroesophageal variceal rebleeding. Methods Sixty-two patients with recent gastroesophageal variceal bleeding were treated by PSE with Seldinger technique. All the patients were followed-up for 12 months. The data including peripheral blood cell count, liver function, plasma prothrombin time (PT), portal vein diameter, and appearance of gastroesophageal varices under gastroscopy were collected before and after embolization for statistical analysis. Results Five days after the operation, the numbers of leucocytes and platelets were significantly increased (P<0.05), and PT was significantly shortened (P<0.05). All the patients showed a good response after PSE with reduced internal diameter of the portal vein and blood flow (P<0.05). Gastroesophageal varices were relieved in all the patients. Rebleeding occurred in 11 patients during the follow-up. Conclusion PSE can be effective in preventing gastroesophageal variceal rebleeding.更多还原