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炎症因子对冠心病易损斑块的预测价值

Predictive Value of Inflammatory Factors on Vulnerable Plaque of Coronary arteries Disease

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【作者】 许道营张秀洲宗立庚刘爱国姜凤芹张玲玲步芳芳

【Author】 Xu Dao-ying,Zhang Xiu-zhou,Zong Li-geng,et al. (Department of Healthcare,Binzhou People’s Hospital,Binzhou 256610,China)

【机构】 滨州市人民医院干部保健科

【摘要】 目的:探讨炎症因子对冠心病(CHD)易损斑块的预测价值。方法:选择住院的CHD患者121例作为研究对象,通过冠状动脉造影(CAG)结果观察斑块性质,分为易损斑块组(A组)与稳定斑块组(B组),测定各组患者血清炎症因子(IL-6、sICAM-1、MMP-9、CRP)水平并进行比较。结果:A组血清炎症因子显著高于B组(P<0.01);AMI及UAP组血清炎症因子显著高于SAP组(P<0.01)。结论:可以通过测定循环血液中的炎症因子来预测CHD患者冠状动脉斑块的易损性。

【Abstract】 Objective:To observe the predictive value of inflammatory factors on vulnerable plaque of coronary arteries disease. Methods:Select patients with coronary heart disease diagnosis as the observed object.The plaque nature was observed through coronary angiography(CAG) and the serum inflammatory factors(IL-6,sICAM-1,MMP-9,CRP) were measured.The results were compared in each group.Results:AMI and UAP serum inflammatory cytokines were significantly higher than SAP Group(P<0.01);Vulnerable plaque group serum inflammatory cytokines were significantly higher than the stability of plaque group(P<0.01).Conclusion:We can predict the vulnerable plaque through the serum inflammatory factors in coronary arteries disease.

  • 【文献出处】 中国医药导刊 ,Chinese Journal of Medicinal Guide , 编辑部邮箱 ,2010年02期
  • 【分类号】R541.4
  • 【被引频次】1
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