【摘要】 目的:评价高蛋白肠内营养(EN)制剂对老年脑卒中病人营养状况的影响。方法:将104例老年脑卒中病人随机分为高蛋白EN组和标准EN组,每组52例。于入院营养支持前、营养支持第1和第2周分别检测两组病人的空腹血糖(Glu)、Hb、血清总蛋白(TP)、清蛋白(ALB)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)等水平,观察病人营养支持过程中胃肠道不良反应的发生情况和患病3个月内生存率和病死率。结果:两组病人营养支持第1周TP、ALB、Hb和HDL均下降,高蛋白EN组Glu、TG升高,标准EN组TG、TC、LDH下降。高蛋白EN组病人Hb、TG、TC和LDL均高于标准EN组,营养支持第2周ALB就回升,TG和HDL下降;而标准EN组TP、ALB、TC和HDL继续下降。高蛋白EN组低蛋白血症的发生率明显低于标准EN组。两组病人胃肠道并发症和3个月生存率无显著性差异。结论:高蛋白EN制剂可改善老年脑卒中病人的营养状况,减少低蛋白质血症的发生率。更多还原

【Abstract】 Objective: To evaluate the effect of high-protein enteral nutrition on nutritional status in elderly stroke patients.Methods: 104 cases of elderly stroke patients(age≥60) were randomly devided into high-protein enteral nutrition group(high-protein group,52 cases) and standard enteral nutrition group(standard group,52 cases).All patients were treated by conventional therapy.The levels of blood glucose,hemoglobin,serum total protein,albumin,triglyeride,total cholesterol,high density lipoprotein,low-density lipoprotein and gastrointestinal side effects were measured before and at the 1st week,the 2nd week after enteral nutrition.The number of survival and deaths within 3 months were counted.Results: The levels of serum total protein,albumin,hemoglobin and high density lipoprotein in two groups were decreased at the 1st week after enteral nutrition.The levels of blood glucose and triglyeride were increased in high-protein group.The levels of triglyeride,total cholesterol and low-density lipoprotein were decreased in standard group.The levels of hemoglobin,triglyeride,total cholesterol and low-density lipoprotein were higher in high-protein group than those in standard group.The level of albumin in high-protein group was increased,however the levels of triglyeride and high density lipoprotein in high-protein group were decreased at the 2nd week after enteral nutrition.The levels of serum total protein,albumin,total cholesterol and high density lipoprotein were decreased in standard group at the 2nd week after enteral nutrition.The incidence of hypoproteinemia in high-protein group was lower than that in standard group.The gastrointestinal side effects and three-month survival rate in two groups were not different.Conclusion: High-protein enteral nutrition support can significantly improve nutritional status in elderly stroke patients.更多还原