【摘要】 为了得到基于相位检测、角度检测和波长检测的表面等离子体共振(SPR)生物传感器的高检测精度,利用Matlab建立了Kretschmann模型SPR传感器的数值仿真软件。系统地进行了棱镜折射率、测试介质折射率、金膜的厚度等因素对3种不同检测方式的SPR曲线的影响。理论分析结果表明:角度调制时与介质折射率增加时,SPR角也相应增加,相位检测对传感层的折射率具有选择性。更多还原

【Abstract】 To realize high detection precision of surface plasmon resonance( SPR) biosensor based on phase detection,angle detection and wavelength detection,numerical simulation software for SPR sensor with Kretschmann model was set up using Matlab. Effect of refractive index ( RI) of prism,RI of sample and the thickness of Au thin film on SPR curve of three different detecting method is described. Theoretical analysis results show that the SPR angle increase with the increase of RI of sample when the angle modulation. The phase detection has selectivity to the refractive index of the sensing layer.更多还原