【摘要】 目的:探讨成人口咽部狭窄部位长度与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的发病、严重程度及口咽部可塌陷程度的相关性。方法:选择经多导睡眠(PSG)检查符合OSAHS的成人患者30例,记录患者的睡眠呼吸暂停低通气指数(AH I)、最低SpO2;经螺旋CT进行口咽部扫描,测量狭窄部位长度(L);并利用电子喉镜观测狭窄部位在Müller动作下塌陷程度(D)。分析L分别与AH I、最低SpO2、Müller动作下口咽部塌陷程度(D)的相关关系。结果:成人口咽部狭窄部位长度为27.42±5.74 mm,多为咽腔的异常结构导致;AH I、最低SpO2、D与L在统计学上有显著相关关系,AH I与L的相关系数为0.624(P<0.01),最低SpO2与L的相关系数为-0.470(P<0.01)。结论:AH I、最低SpO2、D与L之间存在明显的相关性,运用多层螺旋CT进行口咽部动态扫描并辅以电子喉镜形态观察可有效判断OSAHS患者口咽部咽腔狭窄程度及咽腔异常结构,为临床诊断和治疗该疾病提供理论依据与技术参数。更多还原

【Abstract】 Objective: To explore the possible correlation of the length of stricture pharyngeal tissue with the morbidity and severity of Obstructive Sleep Apnea-Hypopnea Syndrome(OSAHS) and its collapsibility.Methods: Thirty patients with OSAHS who has been performed polysomnography(PSG) were selected,and their apnea hypopnea index(AHI) and the lowest SpO2 were recorded.All patients were scanned with CT to get the length of stricture retropharyngeal tissue(L).And they were all performed electrolaryngoscope and Müller test to determine the collapse degree of narrow pharyngeal cavity(D).Results: The length of stricture pharyngeal tissue was 27.42±5.74 mm,which was caused by the abnormal anatomical structure of pharynx.AHI,the lowest SpO2 and D were significantly correlated with L.The correlation coefficient for AHI and L,the lowest SpO2 and L were 0.624(P<0.01) and-0.470(P<0.01),respectively.Conclusion: AHI,the lowest SpO2 and D were associated with L.Spiral CT and Electrolaryngoscopy can effectively determine the abnormal structure and the narrow degree of pharyngeal cavity in the patients with OSAHS,which can provide the theoretical foundation and technique parameters for the diagnosis and treatment of the disease.更多还原