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甲型H1N1流感重症病例临床及肺部影像特征分析(附3例报告)
CLINICAL AND IMAGEOLOGICAL FEATURES OF LUNG IN SEVERE H1N1 INFLUENZA A:A REPORT OF THREE CASES
【摘要】 目的提高对甲型H1N1流感重症病例肺部影像特征认识。方法分析3例甲型H1N1流感重症病例的临床资料,并对其肺部影像学特征进行分析。结果 3例病人胸部CT显示不同程度肺损伤。例1胸部CT表现左侧肺部中、下叶大片渗出性致密阴影,右肺下叶可见少许渗出性阴影,边界不规则。例2胸部CT表现为右侧肺下叶渗出性阴影,散在性多发病灶。例3胸部CT表现为双侧肺上中下渗出性病灶,以中下叶为主。3例临床均表现为发热、咳嗽和胸闷症状,低氧血症以及白细胞减少。3例均给予抗生素和奥司他韦治疗,效果良好,康复出院。结论甲型H1N1流感重症病例肺部影像表现为以双侧中下叶为主的多发病灶,以渗出性阴影为主,间或少许间质改变,病灶呈多样性变化为特点,进展迅速。抗炎抗病毒治疗后吸收良好。
【Abstract】 Objective To raise the understanding of lung image features in severe patients with influenza A H1N1.Methods An analysis was done for clinical data of three patients with severe H1N1 influenza A and their features of lung image.Results A chest CT scan of the three patients showed various extents of lung injuries: In case 1,massively exudative dense shadow of middle and lower lobes of left lung,and a little effusion of lower lobe in the right lung with irregularity boundary could be seen;In case 2,exudative shadow in lower lobe of right lung,characterized as disseminate multiple lesions;In case 3,exudative focus in bilateral lungs,with mainly in middle and lower lobe.The manifestations of those three cases were the same: fever,cough,chest distress,hyoxemia,and leucopenia.They were given antibiotics and oseltamivir with a good outcome and rehabilitation discharged. Conclusion The main manifestations of lung on CT in patients with severe H1N1 influenza A are multiple lesions in middle and lower lobes of bilateral lungs with fast development,which characterized mainly as effusion or a little mesenchymal changes.The lesions respond well to anti-inflammatory and antiviral therapy.
【Key words】 influenza A virus,H1N1 subtype; pneumonia; tomography,X-ray computed;
- 【文献出处】 青岛大学医学院学报 ,Acta Academiae Medicinae Qingdao Universitatis , 编辑部邮箱 ,2010年06期
- 【分类号】R511.7;R816.41
- 【被引频次】3
- 【下载频次】62