【摘要】 目的观察10 d序贯疗法根治幽门螺杆菌(Hp)感染的效果与安全性。方法选取80例Hp阳性病例,随机分为2组。治疗组给予10 d序贯疗法,对照组给予传统三联疗法,疗程10 d。疗程结束1月后行14C尿素呼气试验检测。结果治疗组疗效显著优于对照组(uc=2.28,P<0.05);治疗组14C尿素呼气试验转阴率为95%,对照组为75%,两组比较差异有显著性(χ2=6.27,P<0.05)。结论 10 d序贯疗法根除Hp的效果较传统三联疗法好。更多还原

【Abstract】 Objective To assess the efficacy and safety of 10-day sequential therapy for eradication of helicobacter pylori(Hp). Methods Eighty patients with Hp-positive were divided into two groups in random.Treatment group,10-day sequential therapy was offered;Control group,triple therapy was given.The course was 10 days for the both groups.14C urea breath test was conducted one month after completion of the therapy. Results The therapeutic efficacy was much better for those in the treatment group than those in the control,the breath test showed negative rate of 95% for treatment group,and 75% for the control,being significant difference between the two groups(χ2=6.27,P<0.05). Conclusion For Hp eradication,10-day sequential therapy is more effective than triple therapy.更多还原