【摘要】 目的观察胸/腹腔灌注维拉帕米及化疗药物的疗效和毒副作用。方法57例恶性胸/腹腔积液,胸腹腔联合灌注维拉帕米及化疗药物,1个周期治疗后评价疗效及毒副反应。结果胸/腹腔灌注的有效率(CR+PR)为89.5%,其中胸水的总有效率(CR+PR)为88.9%,腹水的总有效率(CR+PR)为90.0%。Ⅰ度胃肠道反应(42.1%),2例II度消化道反应,灌注部位轻度疼痛(22.8%),发热(19.3%),白细胞下降(10.5%)。结论维拉帕米联合化疗药物胸/腹腔灌注可以提高胸腹水治疗的有效率。更多还原

【Abstract】 Aim To observe the therapeutic effect of therapeutic alliance of verapamil and chemotherapeutics splanchnocoel perfusion.Methods 57 hydrothorax and seroperitoneum were splanchonocoel perfused with verapamil and chemotherapeutics,therapeutic effect evaluated after 2 courses of treatment.Results The general effective rate of splanchnocoel perfusion was 89.5%,including hydrothorax 88.9% and seroperitoneum 90.0%.The incidence of untoward reaction were nausea and vomiting 42.1%,mild pain 22.8%,fever 19.3%,leucocyte decrease 10.5%.Conclusion Therapeutic alliance of verapamil and chemotherapeutics splanchnocoel perfusion could increase therapeutic effective rate of hydrothorax and seoperitoneum.更多还原