【摘要】 目的探讨血浆同型半胱氨酸(hemocysteine,Hcy)水平与颈动脉粥样硬化及脑梗死的关系。方法 126例动脉粥样硬化性脑梗死患者为脑梗死组,选择同期健康体检者82例为对照组。检测两组患者的血浆同型半胱氨酸水平,并应用超声检查颈动脉内膜-中层厚度(intimal-medial wall thickness,IMT)。结果脑梗死组患者血浆Hcy、IMT均显著高于对照组,差异有统计学意义(P<0.05);患者的血浆Hcy水平与IMT呈正相关(r=0.70,P<0.05)。结论血浆Hcy水平与颈动脉粥样硬化关系密切,是动脉粥样硬化性脑梗死的独立危险因素。更多还原

【Abstract】 Objective To investigate the relationships among plasma homocysteine(HCY),carotid atheroscleros is and cerebral infarction.Methods 126 patients were chosen for the atherosclerosis and cerebral infarction(CI)group and 82 healthy people for the control group.The levels of plasma HCY were measured.All groups were examined the changes of carotid intimal-medial thickness(IMT)by carotid duplex ultrasonography scanning.Results The plasma level of homocysteine was significantly higher in the atherothrombotic cerebral infarction than that in the control group(P<0.05);The levels of Hcy were correlated with the IMT(P<0.05).Conclusion Plasma Hcy Ievel has a close relation with carotid atherosclerotic plaque,between Hcy and High lavel of Hcy may be the risk factor of carotid atherosclerotic更多还原