【摘要】 目的探讨强化阿托伐他汀治疗急性冠脉综合征(ACS)的临床疗效,观察超敏C-反应蛋白(Us-CRP)及血脂水平的变化。方法选择65例急性冠脉综合征患者于治疗前,及治疗后4周、12周、24周检测Us-CRP和血脂水平,对比分析,并与健康对照组34例Us-CRP进行对比。结果 ACS患者治疗后4周、12周、24周后Us-CRP、总胆固醇、低密度胆固醇、三酰甘油均明显降低(P(0.01),高密度胆固醇有明显升高(P(0.01)。结论坚持强化阿托伐他汀治疗ACS能提高患者降脂治疗达标率,且持续降低患者血清超敏C反应蛋白,抑制斑块内炎症反应。更多还原

【Abstract】 Objective To probe into curative effect of acute coronary syndrome (ACS) by Intensive atorvastatin therapy,and to be observed the change Ultrasensitive C-reactive protein(Us-CRP)and Lipids Levels.Methods 65 ACS patients were assessed by detecting Us-CRP and lipids levels at before therapy,and after therapy 4th week,12th week and 24th week,and also compared Us-CRP with 34 healthy persons.Results Us-CRP,The total cholesterol,low density lipoprotein cholesterol,and triglyceride of ACS patients are all reduced(P﹤0.01)after therapy 4 weeks,12 week and 24 weeks,high density lipoprotein cholesterol is increased(P﹤0.01).Conclusion To persevere in intensive atorvastatin therapy increased the rate of reaching the Lipoprotein regulating goal of ACS patients,and continually reduced Us-CRP,and control plaque inflammation.更多还原