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复方消经痛胶囊致突变性研究
Study on mutagenicity of fufang xiaojingtong capsules
【摘要】 目的:研究复方消经痛胶囊的致突变性。方法:采用小鼠精子畸形试验、骨髓嗜多染红细胞微核试验和小鼠睾丸染色体畸变试验,观察其致突变性。结果:复方消经痛胶囊的小鼠精子畸形试验,骨髓嗜多染红细胞微核试验和小鼠染色体畸变试验结果均为阴性。结论:在本实验条件下,未发现复方消经痛胶囊的致突变性。
【Abstract】 OBJECTIVE:To study the mutagenicity of Fufang Xiaojingtong capsules (FFXC).METHODS:The mouse sperm morphology test,the mouse sperm chromosomal aberration test and the mouse bone marrow micronucleus test were used to evaluate mutagenicity of FFXC.RESULTS:The results of sperm morphology rates,the sperm chromosomal aberration test and the bone marrow micronucleus rates were negative.CONCLUSION:FFXC had no mutagenic effects in our study.
【关键词】 复方消经痛胶囊;
突变性;
精子畸形试验;
睾丸染色体畸变试验;
微核试验;
【Key words】 Fufang Xiaojingtong capsule; mutagenicity; sperm abnormality test; sperm chromosomal aberration test; micronucleus test;
【Key words】 Fufang Xiaojingtong capsule; mutagenicity; sperm abnormality test; sperm chromosomal aberration test; micronucleus test;
【基金】 河北省科技攻关课题(04276101D-50)
- 【文献出处】 癌变.畸变.突变 ,Carcinogenesis,Teratogenesis & Mutagenesis , 编辑部邮箱 ,2010年01期
- 【分类号】R286
- 【被引频次】2
- 【下载频次】67