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夏天无总碱对家兔血液流变性及血小板聚集的影响
Effect of total alkaloids from Rhizoma Corydalis Decumbeutis on blood viscosity and platelet aggregation in rabbits
【摘要】 目的:探讨夏天无总碱对家兔血液流变性及血小板聚集的影响。方法:测定静脉注射夏天无总碱对家兔血黏度和血小板聚集的影响。结果:夏天无总碱0.1,0.2,0.4mg/kg可显著降低家兔全血粘度、红细胞压积和红细胞聚集指数,抑制二磷酸腺苷(ADP)、花生四烯酸(AA)和胶原诱导的家兔血小板聚集。结论:夏天无总碱具有改善家兔血液流变性,抑制血小板聚集的作用。
【Abstract】 Object:To study the effects of total alkaloids from Rhizoma Corydalis Decumbeutis (TARCD) on blood viscosity and platelet aggregation in rabbits. Methods: Blood viscosity and platelet aggregation were measured after intravenous injection of TARCD in rabbits. Results: TARCD significantly reduced plasma and serum viscosity in rabbits, inhibited platelet aggregation induced by ADP, AA and collagen. Conclusion: TARCD possessed the ability of improving blood viscosity and inhibiting platelet aggregation.
【关键词】 夏天无总碱;
血液流变性;
血小板聚集;
【Key words】 total alkaloids from Rhizoma Corydalis Decumbeutis; blood viscosity; platelet aggregation;
【Key words】 total alkaloids from Rhizoma Corydalis Decumbeutis; blood viscosity; platelet aggregation;
- 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,2009年03期
- 【分类号】R285
- 【被引频次】13
- 【下载频次】227