【摘要】 目的探讨妊娠期间母体与血清热休克蛋白之间的关系。方法用双抗体夹心ELISA法检测114例孕妇血清热休克蛋白含量,按孕3、5、7、8个月和足月共分五组,与非孕对照组比较。结果孕3-8个月组血清HSP70蛋白的含量与非孕对照组比较无差异(P>0.05),足月孕妇组血清HSP70含量明显升高,与非孕对照组比较有非常显著性差异(P<0.001);重度妊高征患者血清热休克蛋白70含量明显高于同孕龄正常孕妇组(P<0.001)。结论了解不同孕月健康孕妇血清HSP70含量,可为妊娠期间某些疾病引起的血清HSP70升高,提供参考依据。更多还原

【Abstract】 Objective:The study attempts to see the relation between mother nuclide and serum heat shock protein during gestational period.Methods: The contents of serum heat shock protein of 114 pregnant women have been tested with the double-antibody solid-phase technique ELISA.Five groups are divided: 3-month,5-month,7-month,8-month and full term.The results are compared with that of the non-pregnant group.Findings: No difference has been found in the content of the serum HSP70 protein in 3-8 month groups(P>0.05);There is a sharp rise in the content of the serum HSP70 protein in the full term pregnant group.Clear distinctness exists compared with the non-pregnant group(P<0.001);The content of the serum HSP70 protein of the patients with the severe pregnancy-induced hypertension syndrome is much higher than that of the normal pregnant group of the same gestational age.Conclusion: The content of the serum HSP70 protein of different gestational ages can provide reliable basis for some diseases causing the rise of serum HSP70 during gestational period.更多还原