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托烷司琼对子宫全切患者术后镇痛引起恶心呕吐预防作用的临床研究

The clinical study of the prevention effect of nausea and vomiting of tropisetron in postoperative total uterectomy patients venously analgecised by fentanyl

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【作者】 杨仁王鹏宇何杰郦正阳

【Author】 YANG Ren,WANG Pengyu,HE Jie,LI Zhengyang (the People’s Hospital of Zhuji,Zhejiang 311800,China)

【机构】 诸暨市人民医院

【摘要】 目的:探讨托烷司琼对子宫全切患者芬太尼静脉术后镇痛引起恶心呕吐的预防作用。方法:收集我院子宫全切术后应用芬太尼静脉自控镇痛(PCVA)患者150例,分为实验组与对照组,实验组(75例)术后镇痛配方为芬太尼1.2mg,托烷司琼5mg加生理盐水至240ml,对照组(75例)镇痛配方中不加托烷司琼。结果:实验组患者恶心呕吐的发生率(9.33%)明显低于对照组(45.33%),两组比较x~2=24.4686,P<0.01;实验组不良反应的发生率(12.00%)明显低于对照组(25.33%),两组比较x~2=4.3911,P<0.05。结论:托烷司琼用于子宫全切术后患者,可对镇痛引起的恶心呕吐进行积极预防,疗效明显,适合在临床推广应用。

【Abstract】 [Objective]To investigate the prevention effect of nausea and vomiting of tropisetron in postoperative total uterectomy patients venously analgecised by fentanyl.[Method]One hundred and fifty total uterectomy patients analgecized by fentanyl through patient - contolled venous analgesia(PCVA) have been divided into two groups.1.2mg of fentanyl and 5mg of tropisetron added by saline up to 240 ml was prepscribed to study group(75 cases).In the contrast group(75 cases) there is no tropisetron.[Result]The rate of nausea and vomiting in the study group(9.33%) is statistically lower than that of the constrast group(45.33%).X2 = 24.4686,P< 0.01.The rate of adverse reaction in the study group(12.00%) is statistically lower than that of the constrast group(25.33%).X2 = 4.3911,P<0.05,[Conclusion]tropisetron effectively prevented the side effect of nausea and vomiting induced by analgesia in postoperative total uterectomy patients.The curative effect is remarkable and is suitable to be popularized clinically.

  • 【文献出处】 浙江医学教育 ,Zhejiang Medical Education , 编辑部邮箱 ,2009年03期
  • 【分类号】R614
  • 【下载频次】10
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