【摘要】 目的:探讨原发性肾病综合征患者(PNS)凝血4项指标的临床价值。方法:选择72例PNS患者,以60例健康体检者作为对照,按要求留取血浆标本。在贝克曼公司ACL-ADVANCE全自动血凝仪上测定凝血酶原时间(PT)、部分活化凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)4项指标;留取血清标本,在日立7180全自动生化分析仪上测定甘油三酯(TG)、总胆固醇(TG)、高密度脂蛋白(ADL)、低密度脂蛋白(LDL-C),并计算HDL.-C/TC比值.结果:PNS组与对照组比较,除APTT外差异均有统计学意义(P<0.01),PT明显低于对照组,血TT、FIB高于对照组。血TC、TG、HDL-C、LDL-C明显高于对照组,HDL/TC明显低于对照组,结论:原发性肾病综合征患者血液呈高凝状态,及时检测凝血4项指标,同时监测血脂4项指标有利于及早预防并发症的发生。更多还原

【Abstract】 [Objective]This article aims to investigate the clinical significance of four coagulation markers in primary nephritic syndrome(PNS).[Method]PT、APTT、TT、FIB level was measured by ACL- ADVANCE in 72 PNS and 60 normal subjects. TC、TG、HDL、LDL level was measured by HITACHI 7180 in 72 PNS and 60 normal subjects.[Result]FT and HDL/TC level in PNS group was significantly decreased as compared with normal subjects group;TT,FIB,TC,TG,LDL- C level in PNS group was significantly higher than that in normal subjects group.[Conclusion]It has been found that PNS patients are in the hypercoagulable state.The measurement of four coagulation markers is of clinical value in the early diagnosis of PNS patient with hypercoagulable state.更多还原