【摘要】 目的探讨肌钙蛋白T测定在急性冠脉综合征(ACS)诊断中的符合程度。方法测定以胸痛、胸闷、心悸为主诉入院的509例患者的血清肌钙蛋白T,统计出临床确诊为ACS患者和临床排除ACS患者其肌钙蛋白T测定结果的比例,以统计阳性率、阴性率、假阴性和假阳性率。结果423例患者(83.1%)结合临床症状和心电图表现被诊断为ACS,其肌钙蛋白T测定>0.7ng/ml的有407例,肌钙蛋白T测定<0.7ng/ml的有16例。86例患者(39%)结合临床症状和心电图表现排除ACS,其中肌钙蛋白T测定>0.7ng/ml为5例,肌钙蛋白T测定<0.7ng/ml的有81例。结论虽然肌钙蛋白T被认为是诊断ACS的特异性指标,但在临床应用中,也存在检验结果和临床诊断不相符的情况。更多还原

【Abstract】 [Objective]To evaluate the consistency of Troponin T level determination in the diagnosis of acute coronary artery syndrome(ACS).[Methods]Troponin T levels of 509 serum samples from patients whose chief complaint were chest pain,chest tightness and palpitation were measured.The positive rate,negative rate,false negative and false positive rate were calculated according to the Troponin T measurements ratio of ACS to non-ACS confirmed by clinical diagnosis.[Results]A total of 423 patients(83.1%) were finally confirmed as ACS by combination of clinical manifestation and electrocardiogram result,among which 407 patients’ serum samples showed a high Troponin T level(>0.7ng/ml).16 patients’ Troponin T levels were <0.7 ng/ml.86 patients(39%) excluded ACS by combination of clinical manifestation and electrocardiogram result,among which 5 patients’ Troponin T levels were >0.7 ng/ml,81 on the contrary.[Conclusion]Troponin T level is considered as a specificity index of the diagnosis of ACS,however,inconsistency between test results and clinical diagnosis exists in clinical application.更多还原