【摘要】 目的:观察中西医结合疗法对高血压晨峰现象控制的效果并进行评价。方法:2006年9月—2007年8月选取本院住院期间具晨峰现象的高血压患者85例,随机分为治疗组和对照组,对照组患者每天晨起口服氨氯地平(络活喜)片剂5mg,苯那普利(洛汀新)片剂10mg;治疗组在此基础上加用杞菊地黄口服液每次10mL,1日3次,共治疗2月。结果:治疗2月后,治疗组、对照组醒后2h血压(SBP)较治疗前下降,有统计学差异(P<0.05),治疗组的晨峰血压SBP较治疗前下降,差异有统计学意义(P<0.05);对照组的有效率为80.9%,治疗组的有效率为95.3%,治疗组的有效率比对照组高,差异有统计学意义(P<0.05)。结论:中西医结合疗法在控制高血压晨峰方面疗效优于单纯西医疗法,中医抗高血压晨峰的具体机制尚待进一步研究。更多还原

【Abstract】 Objective:To observe and evaluate the regulation effect of the treatment of integrated traditional Chinese and western medicine on decreasing morning blood pressure surge(MBPS).Methods:conforming eighty inpatients with MBPS were randomized to control group and treatment group.Patients received amlodipine(5mg/d) and benazepril(10mg/d) in control group for two weeks.While Patients received amlodipine(5mg/d),benazepril(10mg/d) and QiJu DiHuang oral liquid(60mL/d) for two weeks.Before and after treatment patients were measured by 24 hour ambulatory blood pressure monitoring(ABPM).Results:Comparing to two months ago the significant decrease of average SBP of 2 hours both before and after awake was observed in two groups(P<0.05).The significant decrease of MBPS’ SBP was observed in treatment group(P<0.05).A higher effective rate was observed in treatment group(95.3%) than in control group(80.9%).Conclusion:A better efficiency for decreasing MBPS was observed in treatment group than in control group.更多还原