【摘要】 目的评价肺癌患者血清肿瘤标志物癌胚抗原(CEA)、糖类抗原153(CA153)、糖类抗原125(CA125)联合检测的临床意义。方法以135例肺癌患者、130例肺部良性疾病患者、130例健康人为研究对象,采用化学发光法检测其血CEA、CA153及CA125水平。结果肺癌组血清CEA、CA153及CA125的水平明显高于肺部良性病变组和健康对照组(P<0.01),三项联合测定的敏感度(80.2%)和准确性(85.2%)均明显高于单一检测。结论血清肿瘤标志物联合检测有助于肺癌的临床诊断。更多还原

【Abstract】 Objective To evaluate the clinical significance of detecting CEA,CA153 and CA125 in serum of patients with lung cancer.Methods CEA,CA153 and CA125 levels in blood from 65 patients with lung cancer were detected;60 patients with other lung diseases and another 50 normal subjects were performed chemiluminescent immunoassay,respectively. Results The contents of serum CEA,CA153,CA125 in lung carcinoma patients were significantly higher than that in patients with benign lung disease and healthy controllers(P < 0.01).The sensitivity(80.2%) and accuracy(85.2%) of the combined determination were significantly higher than single assay.Conclusion The combined determinotion of three tumormarkers could be helpful for the diagnosis in patients with lung cancer.更多还原