【摘要】 目的:研究以乙醇为溶剂从元宝枫叶中提取抑制脂肪酸合酶的多酚类物质的工艺条件。方法:采用L16(45)正交试验,以提取时间、温度、溶剂组成和固液比为考察因素,以多酚的提取率以及对脂肪酸合酶的抑制率为检测指标,经过综合加权评分后得到优化提取工艺。结果:优选的提取工艺是乙醇体积分数为60%,固液比1g∶30mL,在50°C条件下,搅拌提取1.5h。结论:多酚类物质对脂肪酸合酶有抑制作用,从元宝枫叶中提取的某些多酚类物质具有相对较强的抑制作用。更多还原

【Abstract】 Objective: To optimize a technical process for extracting the polyphenols that can inhibit fatty acid synthase by ethanol from the leaves of Acer truncatum.Methods:The extracting time,extracting temperature,extracting solvent and the ratio of solvent to raw material were studied by L16(45) orthogonal experiments.The extraction rate of polyphenols and the inhibitory efficiency on the fatty acid synthase were utilized as evaluating criteria,and the optimum conditions for the extraction were obtained through summing up the above factors.Results: The efficient technological conditions were as follows: the concentration of ethanol was 60%(v/v),the ratio of solvent to raw material was 1g∶30mL;and the stirring time was 1.5h at 50°C.Conclusion: The polyphenols that extracted from the leaves of Acer truncatum have inhibitory activity against fatty acid synthase and some of them have stronger inhibitory effect.更多还原