【摘要】 目的:探讨青少年抑郁症与行为抑制/激活系统的关系。方法:采用行为抑制/激活系统问卷、Beck抑郁问卷和Zung氏抑郁自评问卷测评27名青少年抑郁症、38名抑郁情绪青少年及健康对照组74名青少年,比较3组青少年在行为抑制/激活系统得分上的差异,并做抑郁与行为抑制/激活系统的相关分析。结果:(1)抑郁症组和抑郁情绪组的行为抑制系统得分均高于无抑郁组[(14.6±2.4),(14.5±1.5)vs.(13.3±1.5);P<0.001],而行为激活系统的奖赏反应和驱力得分均低于无抑郁组[奖赏反应:(11.7±1.7)、(12.4±1.7)vs.(12.7±2.0),(10.1±1.8)、(10.3±1.9)vs.(11.2±1.9);P<0.05或0.01];(2)抑郁症组抑郁得分与行为抑制/激活系统呈不同程度的相关(r=-0.26-0.84,P<0.05或0.01)。结论:行为激活系统功能降低、行为抑制系统功能增强可能是抑郁症的危险因素。更多还原

【Abstract】 Objective:To explore the relationships between adolescent depression and behavioral inhibition/activation systems.Methods:Twenty-seven adolescents with major depression(MD),38 adolescents with depressive moods,and 74 healthy adolescents were assessed with the Behavioral Inhibition/Activation System Scale(BIS/BAS Scale),Beck Depression Inventory(BDI) and Zung Self-Rating Depression Scale(SDS).The differences of BIS/BAS among the three groups were compared and the correlations between depression and BIS/BAS were analyzed.Results:(1) Compared with healthy adolescents,adolescents with major depression and depressive moods scored higher in BIS [(14.6±2.4),(14.5±1.5)vs.(13.3±1.5);P<0.01]and lower in BAS-reward and BAS-drive [BAS-reward:(11.7±1.7),(12.4±1.7) vs.(12.7±2.0),BAS-drive:(10.1±1.8),(10.3±1.9) vs.(11.2±1.9);Ps<0.05].(2) The scores of depression in major depression groups were correlated with BIS/BAS in varying degrees(r=-0.26-0.84,Ps<0.05).Conclusions:Hypoactive BAS and hyperactive BIS may be risk factors for depression.更多还原