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原发性纵隔肿瘤的外科治疗

Surgical treatment on primary mediastinal tumors

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【作者】 刘勇殷桂林胡建才朱水波张晓明王荣平

【Author】 LIU Yong, YIN Guilin, HU Jiancai, ZHU Shuibo, ZHANG Xiaoming, WANG Rongping(Department of Thoracic and Cardiovascular Surgery, Wuhan General Hospital of Guangzhou Command, Wuhan, Hubei 430070, P.R.China)

【机构】 广州军区武汉总医院心胸外科

【摘要】 目的总结原发性纵隔肿瘤的外科治疗经验。方法回顾分析该院1998年1月~2008年7月收治并经病理证实的85例原发性纵隔肿瘤患者的临床资料。结果全组男性50例,女性35例,年龄4~75岁,平均41岁。包括:胸腺瘤29例(34.1%),生殖细胞源性肿瘤13例(15.3%),神经源性肿瘤12例(14.1%),胸内甲状腺肿8例(9.4%),淋巴瘤5例(5.9%),原发囊肿12例(14.1%),其他肿瘤6例(7.1%)。总手术切除率为95.3%(81/85)。全组无手术死亡。术后胸腺瘤合并肌无力者出现肌无力危象3例。术后随访的59例患者(69.4%),随访时间1个月~5年。良性纵隔肿瘤患者术后均预后良好,有3例恶性胸腺瘤患者分别在术后3个月、2年、3年复发并转移,因死于癌肿复发及其引起的各种并发症而死亡。结论原发性纵隔肿瘤不论良性还是恶性,只要无明确手术禁忌,均应及早手术。

【Abstract】 Objective To summarize the surgical experience of primary mediastinal tumor.Methods The clinical data of 85 patients with mediastinal tumor who underwent surgical treatment and improved pathologically from Jan.1998 to July 2008 were retrospectively analyzed.Results There were 50 males and 35 females which aged from 4 to 75 and averaged 41.There were 29 cases(34.1%) with thymoma, 13 cases(15.3%) with germ cell tumor, 12 cases(14.1%) with neurogenic tumor, 8 cases(9.4%) with intrathoracic goiter, 5 cases(5.9%) with lym-phoma, 12 cases(13.1%) with primary cyst and 6 cases(7.1%) with other tumors.The total surgical resection rate was 95.3%(81/85).There was no perioperative death.3 patients with thymoma and myasthenia gravis suffered with myasthenia crisis post-operation.59 cases(69.4%) were followed-up from 1 month to 5 years.Those with benign mediastinal tumors had good prognosis.Three patients with malignant thymoma died of tumor relapse and complications 3 months, 2 years and 3 years later respectively.Conclusion sIf there is no surgical contradiction, operation should be undergone on both benign and malignant primary mediastinal tumors.

【关键词】 原发性纵隔肿瘤外科手术
【Key words】 primarymediastinal tumorsurgery
  • 【文献出处】 中国现代医学杂志 ,China Journal of Modern Medicine , 编辑部邮箱 ,2009年09期
  • 【分类号】R734.5
  • 【下载频次】59
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