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术中植入125I粒子内放疗治疗脑胶质瘤长期疗效观察

Clinical study of long term therapeutic efficacy of brain gliomas treated by interstitial brachytherapy of 125I seeds implanted in operation

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【作者】 尹航杜彦李建华郑秉杰张俊和王立夫

【Author】 YIN Hang1,DU Yan2,LI Jian-hua1,ZHENG Bing-jie1,ZHANG Jun-he1,WANG Li-fu1(1.Department of Neurosurgery,Heilongjiang Provincial Hospital,Harbin,Heilongjiang 150001,P.R.China; 2. Department of Surgery,Harbin Hospital of Truditional Chinese Medicine,Haribin,Heilongjiang,150027,P.R.China)

【机构】 黑龙江省医院南岗分院神经外科黑龙江省哈尔滨市中医医院外科

【摘要】 目的探讨术中植入125I粒子内放疗治疗胶质瘤术后长期疗效。方法将该院近几年胶质瘤患者分为:治疗组(手术切除加瘤巢内放疗组)和对照组(单纯手术切除组),观察2组肿瘤复发时间、生存时间、2年生存率和3年生存率。结果2组复发时间及生存时间比较,治疗组肿瘤复发时间明显延长。治疗组较对照组2年生存率和3年生存率均明显提高。结论术中植入125I粒子内放疗治疗胶质瘤,长期疗效良好,是一种安全有效的治疗脑胶质瘤的方法。

【Abstract】 【Objective】The aim of this protocol was to investigate long term therapeutic efficacy of malignant brain gliomas treated by interstitial brachytherapy of 125I seeds implanted in operation prospectively.【Methods】Pa-tients were devided into tested group and control group. We tested the death rate,the time of life and the time of recurrence.【Results】In tested group compared with control group,we found the death rate decreased and the time of life evidently extended.【Conclusions】Interstitial brachytherapy of 125I seeds implanted in operation can improve the quality of life. It′s an effective method for the treatment of the malignant brain gliomas.

【关键词】 125I粒子脑胶质瘤内放疗
【Key words】 125I seedsgliomainterstitial brachytherapy
  • 【文献出处】 中国现代医学杂志 ,China Journal of Modern Medicine , 编辑部邮箱 ,2009年02期
  • 【分类号】R739.41
  • 【被引频次】1
  • 【下载频次】103
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