【摘要】 目的:研究KCNQ1基因多态性与老年人孤立性、继发性心房颤动的关系。方法:选出老年人孤立性心房颤动患者15例,继发性房颤35例,无心房颤动同期住院患者65例为病房对照组,年轻健康体检对照组100例,应用基因芯片技术检测病例组与对照组KCNQ1基因多态性。结果:在深圳汉族人未发现KCNQ1 G等位基因,各研究组GS GG基因型频率为0。结论:本研究未发现KCNQ1 G等位基因,KCNQ1基因多态性与老年人孤立性、继发性心房颤动无相关性。更多还原

【Abstract】 Objective:To investigate the association of KCNQ1 gene polymorphisms with lone atrial fibrillation or secondary atrial fibrillation in aged people.Methods:The study included 15 lone atrial fibrillation patients and 35 secondary atrial fibrillation in aged people and 65 controls,100 heathy controls.Gene chip was performed.Results:KCNQ1 G alleles was scare.No statistically significant diffence was observed in KCNQ1 genotype distribution.Conclusion:We have not found relationship between KCNQ1 gene polymorphisms and lone atrial fibrillation or secondary atrial fibrillation in aged people.更多还原