【摘要】 目的了解非结核分支杆菌(NTM)肺病对一线抗痨药物的耐药情况,探讨NTM肺病反复发作的原因。方法在本研究所2003-2008年间876例分支杆菌培养阳性的病例中,经鉴定确诊为NTM肺病的资料完整的40例病例进行回顾性分析。结果40例患者中多数对一线抗痨药物(异胭肼,利福平,链霉素)耐药,而对乙胺丁醇的敏感性较好:40例患者中既往"肺结核"病史较长,平均6年,最长达15年:平均治疗次数1.86次,最长达6次。结论对于分支杆菌培养阳性的患者应及早做菌种鉴定,一经确诊应做多种药物的敏感试验,选择最佳联合治疗方案,并坚持全程化疗。更多还原

【Abstract】 Objective To understanding of non-tuberculosis mycobacterium(NTM)lung disease on the first-line anti-TB drug resistance,to explore NTM recurrent disease.Methods In our hospital from 2003 to 2008,876 cases of Mycobacterium culture-positive cases identified by Yin-lung disease diagnosed NTM information complete medical records of 40 cases were reviewed.Results 40 cases of patients in the majority of first-line anti-TB drugs(rouge different hydrazine,rifampicin,streptomycin)resistance,and ethambutol of the sensitivity of better:40 patients in the past,"tuberculosis" a long history,an average of 6 years for a maximum of 15 years,an average of 1.86 times the number of in-patient,for a maximum of 6 times.Conclusion For mycobacterium culture-positive patients as soon as possible should be done to identify bacteria,a diagnosis should be done by multi-drug sensitivity tests to select the best treatment program and insisted that the entire process of chemotherapy.更多还原