【摘要】 目的:了解本地区5岁以下住院腹泻患儿星状病毒(AstV)和轮状病毒(RV)感染情况。方法:收集2008年10月至2009年3月380例5岁以下住院非细菌性腹泻患儿粪便,用酶免法(EIA)检测标本中的星状病毒和轮状病毒抗原。结果:380份标本中,星状病毒和轮状病毒的总阳性率为36.8%(140/380);星状病毒抗原阳性率为16.8%(64/380);轮状病毒抗原阳性率24.5%(93/380);轮状病毒抗原阴性标本中星状病毒抗原阳性率为16.4%(47/287),大多集中在2岁以内占91.2%(59/64)。二者共同阳性占总数的4.5%(17/380)。星状病毒抗原阳性率最高在3月份,为36.2%(17/47),与轮状病毒抗原的高峰期不同。结论:本地区婴幼儿秋冬季腹泻存在较多星状病毒感染,而且也存在星状病毒和轮状病毒同时感染的情况。不同年龄段和气候对不同病毒的易感性存在一定差异。更多还原

【Abstract】 Objective:To study epidemiological features of astrovirus(AstV) and rotavirus(RV) infection in children below the age of 5 years hospitalized for diarrhea in the Chidren′s Hospital of Dalian.Methods:Stool specimens of 380 saved from inpatients of Children′s Hospital of Dalian during the period Octobmer 2008 to March 2009,the antigen of AstV and RV was detected using enzyme-linked immunosorbent assay(ELISA).The target population in this study was children below the age of five,which were negative for bacterial culture.Results:Of 380 samples,36.8%(140/380) were positive for AstV and RV totally;in which 16.8%(64/380) was positive for AstV and 24.5%(93/380)for RV respectively.Of 287 stool specimens negative for RV,AstV was detected in 16.4%,of which 92.1% were from patients of two years old or younger.4.5%(17/380)were positive for AstV and RV together.The peak of the positive rate for AstV was in March 2009 which was 36.2%(17/47),there were differences in the peak time compared with RV.Conclusion:Both RV and AstV are important pathogens which cause viral gastroenteritis in young children in Dalian,but there were differences in viral susceptivity between AstV and RV at climate and age.更多还原