【摘要】 目的:了解福建省志贺菌感染的病原学特征及药敏特点,为细菌性痢疾的防治和临床合理用药提供依据。方法:复核鉴定监测点送检的阳性菌株,按《全国细菌性痢疾监测方案》提供的方法进行系统检测。结果:两年共复核鉴定阳性菌株60株,检出志贺菌41株,其中宋内志贺菌24株,福氏志贺菌17株。分别占检出菌株数的58.5%和41.5%。药敏试验显示,41株志贺菌对头孢噻肟及环丙沙星高度敏感,全部耐药药物为四环素、利福平及复方新诺明。结论:2006~2007年福建省分离的菌株以宋内志贺菌所占比重较大,其次为福氏志贺菌。并对目前常用的抗菌药物表现一定的耐药性,应引起重视。更多还原

【Abstract】 Objective:To discover the etiological characteristics and antimicrobial susceptibility of Shigella spp.in Fujian province,thus providing suggestion for shigellosis prevention and rational prescriptions in clinics.Methods:Positive Shigella isolates from the surveillance sites were systematically re-identified according to National Protocol of Shigellosis Surveillance.Results:60 positive isolates were re-identified,41 Shigella strains were confirmed,including 24 S.sonnei strains and 17 S.flexneri strains,i.e.58.5% and 41.5% respectively.Susceptibility tests indicated that the 41 Shigella strains were highly sensitive to cefotaxime and ciprofloxacin,but resistant to tetracycline,rifampicin and sulfamethoxazole.Conclusion:The dominant Shigella isolates in Fujian from 2006 to 2007 were S.sonnei,the rest were S.flexneri.Meanwhile,it should be concerned that these isolated strains possessed considerable resistance to common antibiotics.更多还原