【摘要】 目的研究氧合血颈动脉灌注在重型颅脑损伤中的作用。方法对28例重型颅脑损伤患者于伤后约3.5天行氧合血颈动脉灌注治疗1周,监测灌注前、中、后的脑组织氧分压(PbtO2)二氧化碳分压(PbtCO2)pH值(pHbt)变化以及伤后3个月格拉斯哥预后评分(GOS)的情况。结果患者经氧合血颈动脉灌注治疗后比治疗前的PbtO2升高(P<0.05),与对照组相比,患者的PbtO2升高,3个月后的GOS改善(P<0.05)。结论氧合血颈动脉灌注在重型颅脑损伤的早期治疗中起着积极和重要的作用。更多还原

【Abstract】 Objective To study the effect of carotid arteries perfusion with oxygenated blood in severe head injury.Methods 28 cases with severe head trauma were treated using carotid arteries perfusion with oxygenated blood for one week after head injury 3.5 days.Before,during and after the treatment,PbtO2,PbtCO2 and pHbt values were evaluated prospectively.In the meantime,Glasgow Outcome Scale(GOS) at the point of three months after injury was observed.Results PbtO2 was elevated after carotid arteries perfusion with oxygenated blood(P<0.05).Compared with control group,PbtO2 was also elevated and GOS improved three months after injury in perfusion group(P<0.05).Conclusion Carotid arteries perfusion with oxygenated blood plays an active and important role in early treatment of severe head injury.更多还原