【摘要】 目的继pH、阴离子隙(AG)后的第三代方程式产生的强离子隙(SIG)的应用,探讨其在肾性低蛋白血症中的临床意义。方法在测定血气、血pH、电解质结果基础上,应用Stewart-Figge方法学的方程式计算SIG。结果(1)比较了SIG、AG及潜在HCO3-等三种诊断指标,以SIG与AG的相关性最好:r=0.967 3。(2)比较肾病患者三种指标,以SIG异常率最高(90.5%);上升幅度最大,是参考值的3.67倍。(3)比较低白蛋白血症肾病与非肾病二组,以SIG的二组差异率最大,为7.42倍,P<0.001。AG及潜在HCO3-次之。结论三种诊断指标以SIG灵敏度最高,若呼吸功能衰竭的酸碱失衡需要潜在HCO3-;而肾功能衰竭的酸碱失衡更需要SIG。更多还原

【Abstract】 Objective Application of thirdly equation-strong ion gap(SIG) that to continue pH、the anion gap(AG) generated,approach clinical significance for SIG on nephritic hypoalbuminemia.Methods SIG is calculated with The Stewart-Figge model,after determination of blood gas、blood pH、serum electrolytes.Results (1)Comparison on AG、potential bicarbonate and SIG,et al Three Diadynamic Criteria,the dependablity to be found SIG to agree well with AG:r=0.967 3.(2)Comparison on Three Diadynamic Criteria,abnormity rate of SIG is best high(90.5%);up grade argument is best high,ratio reference value upper limit is 3.67 times.(3)Comparison of nephropathia and non-nephropathia in Hypoalbuminemia,SIG difference rate is greatest,7.42 times,P<0.001.secondary is AG and potential bicarbonate.Conclusion SIG sensibility is best high in three acid-base imbalance diadynamic criteria,respiratory non-function request to potential bicarbonate,renal failure furthermore request to SIG.更多还原