【摘要】 建立了猪尿中地西泮的气相色谱-质谱(GC/MS)检测方法。样品经C18固相萃取柱净化后进行气相色谱-质谱测定。结果表明,方法定量限为0.5μg/L,线性范围为10~500μg/L。在三个添加浓度2、4、6μg/L水平上,地西泮的平均回收率为70%~120%,批内相对标准偏差<20%、批间相对标准偏差<12%。更多还原

【Abstract】 A gas chromatography-mass spectrometric(GC/MS) method has been established for the determination of diapazem in swine urine.The samples were cleaned up on C18 cartridge,and detected by GC/MS.The results indicated that the limit of quantification(LOQ) was 0.5 μg/L,and the linearity was within the range of 10～500 μg/L.The mean recovery of swine urine samples fortified at three levels of 2,4 and 6 μg/L was within the range of 70%～120%,intra-batch relative standard deviation was less than 20%,and inter-batch relative standard deviation was less than 12%.更多还原