【摘要】 选用1日龄艾维茵健康肉鸡420只,随机分为7组,分别喂以对照日粮(Cu 11 mg/kg)和高铜日粮(Cu 100mg/kg),高铜Ⅰ组,Cu 200 mg/kg,高铜Ⅱ组;Cu 300 mg/kg,高铜Ⅲ组;Cu 400 mg/kg,高铜Ⅳ组;Cu 500 mg/kg,高铜Ⅴ组;Cu 600 mg/kg,高铜Ⅵ组)6周,观察日粮铜添加水平对雏鸡外周血T-淋巴细胞ANAE阳性率的影响。与对照组比较,高铜Ⅰ、Ⅱ组雏鸡外周血T-淋巴细胞ANAE阳性率增加,但差异不显著;高铜Ⅲ、Ⅳ、Ⅴ、Ⅵ组雏鸡外周血T-淋巴细胞ANAE阳性率降低,且与日粮含铜量呈负相关,同时胸腺淋巴细胞减少,凋亡细胞比例增高。结果表明,与对照组比较,日粮铜含量100～200 mg/kg对雏鸡外周血中T-淋巴细胞ANAE阳性率有促进作用,但差异不显著;日粮铜含量300～600 mg/kg程度不同地降低了T-淋巴细胞ANAE阳性率,细胞免疫功能受损。更多还原

【Abstract】 The objective of this experiment was to evaluate effect of high copper on the ANAE positive ratio of the peripheral blood T-lymphocytes in chickens.420 one-day-olg Avian chickens were randomly divided into sever groups,and fed on diets as follows:controls(Cu 11 mg/kg) and high copper(Cu 100 mg/kg,high copper proup Ⅰ;Cu 200 mg/kg,high copper group Ⅱ;Cu 300 mg/kg,high copper group Ⅲ;Cu 400 mg/kg,high copper group Ⅳ;Cu 500 mg/kg,high copper group Ⅴ;Cu 600 mg/kg,high copper group Ⅳ) for six weeks.The results showed that the ANAE positive ratio(%) of the peripheral blood T-lymphocytes in high copper groups Ⅰand Ⅱ had no obvious difference comparied with control group.The ANAE positive ratio(%) of the peripheral blood T-lymphocytes in high copper groups Ⅲ,Ⅳ,Ⅴ and Ⅳwer decreased significantly compared with that of control group.It was concluded that dietary Cu more than 300 mg/kg could decrease the ANAE positive ratio(%) of the peripheral blood T-lymphocytes and impaire cellular immune function in chickens.更多还原