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宫颈癌相关基因单核苷酸多态性的研究进展
Advances in Research of Single-nucleotide Polymorphisms in Genes Associated with Cervical Cancer
【摘要】 在宫颈癌发生过程中,人乳头瘤病毒(human papillomavirus,HPV)感染是必要的环境因素,而宿主遗传易感性则影响感染结局。单核苷酸多态性(SNPs)是新一代的遗传学标记,可用于寻找肿瘤相关基因。本文就宫颈癌相关基因单核苷酸多态性的研究进展做一综述。
【Abstract】 Human papillomavirus infection is the necessary environmental factor in the development of cervical carcinoma, while host genetic predisposition to the disease impact the outcome of infection.Single-nucleotide polymorphisms is the new class of genetic marker, which is widely used to search cancer genes.This review focus on the advances in the research of single-nucleotide polymorphisms in genes associated with cervical cancer in recent years.
【关键词】 宫颈癌;
遗传易感性;
单核苷酸多态性;
【Key words】 cervical cancer; genetic predisposition; single-nucleotide polymorphisms;
【Key words】 cervical cancer; genetic predisposition; single-nucleotide polymorphisms;
- 【文献出处】 中山大学学报(医学科学版) ,Journal of Sun Yat-Sen University(Medical Sciences) , 编辑部邮箱 ,2009年S2期
- 【分类号】R737.33
- 【被引频次】3
- 【下载频次】289