【摘要】 目的探讨脑室-腹腔分流术(V-Ps)后颅内感染的相关危险因素及对策。方法回顾性分析430例施行了分流手术的病例资料,利用Logistic回归分析9项可能相关指标对V-Ps术后感染的影响。结果Logistic回归分析显示感染与术后脑脊液漏、激素和预防性抗生素的应用、手术条件有关。结论本结果有助于预见分流术后感染的危险性,从而减少V-Ps术后感染的发生。抗生素应用基础上移除分流系统,待感染完全控制后再植入新的分流系统是有效的治疗方案。更多还原

【Abstract】 Objective To analyze the relevance of risk factors and preventive strategy of infections after V-Ps.Methods 430 patients with intracranial-infections after V-Ps were retrospectively reviewed to determined the effects of 9 related factors.Results Of the 430 patients,infections were observed in 30 cases(6.98%).Logistic regression analysis showed that the incidence of infection was related to the postoperative leak of CSF,the use of preventive antibiotic and hormore,the operation condition(OR=52.311,0.260,3.325,0.247).Conclusion The results of this study can help in identifying patients with a high risk of infection after V-Ps.The removal of an infected shunt which based on the usage of antibiotic,followed by installation of a new shunt when CSF sterility is achieved,is the effective and reliable method of treatment for CSF shunt infection.更多还原