【摘要】 目的了解广州地区≥15岁人群各类精神障碍的患病率和分布特点。方法2006年8月1～31日采取分层、整群和随机抽样法,使用复合性国际诊断交谈表3.0中文版(CIDI-3.0)对广州地区≥15岁的居民7418人完成访谈,其中"精神病性障碍"筛查阳性者由精神科医生按照美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)轴Ⅰ障碍定式临床检查患者版(SCID-I/P)进行疾病诊断。结果广州地区各类精神障碍加权时点患病率为4.33%,加权终生患病率为15.76%。在加权时点患病率中,排在前三位的是酒精使用障碍(1.38%)、重性抑郁障碍(0.80%)和精神分裂症(0.49%)。各类精神障碍加权时点患病率农村明显高于城市(5.92%vs 3.73%,2=17.12,P<0.001);酒精使用障碍男性明显高于女性(2.54%vs 0.17%,2=86.74,P<0.001)、农村明显高于城市(2.19%vs 0.87%,2=20.65,P<0.001);烟草依赖男性明显高于女性(0.50%vs 0.02%,2=17.78,P<0.001);重性抑郁障碍、广泛性焦虑及未特定抑郁障碍女性明显高于男性(1.03%vs 0.59%,2=4.20,P=0.041;0.53%vs0.16%,2=6.88,P=0.009;0.43%vs 0.13%,2=5.75,P=0.016)。结论广州地区的精神卫生问题值得重视。其中,重性抑郁障碍、酒精使用障碍和精神分裂症患者是社区开展精神卫生服务中的重点人群。更多还原

【Abstract】 Objective To describe the current prevalence and distribution of various types of mental disorders in Guangzhou area.Methods From Aug.1 2006 to Aug.31 2006,a survey of 7418 subjects aged 15 years or over was accomplished in Guangzhou area after stratified cluster randomization,and accessed with the Composite International Diagnostic Interviewer edition 3.0 Chinese version(CIDI-3.0).During this course,for those residents who showed positivity after screening of "psychotic disorder",psychiatrists determined their diagnoses by administering a structured psychiatric examination(SCID-I/P) that employs American diagnostic criteria for mental disorders.Results The adjusted point prevalence rate of mental disorders in Guangzhou area was 4.33%,adjusted lifetime prevalence rate was 15.76%.According to the adjusted point prevalence rate,the most common disorders were alcohol use disorder(1.38%),major depressive disorder(0.80%),and schizophrenia(0.49%).The overall point prevalence was higher in rural than in urban areas(5.92%vs 3.73%,X2=17.12,P<0.001).According to point prevalence,alcohol use disorder was more prevalent in male than in female(2.54%vs 0.17%,X2=86.74,P<0.001),and more prevalent in rural than in urban areas(2.19%vs 0.87%,X2=20.65,P<0.001);Tobacco dependent was higher in male than in female(0.50%vs 0.02%,X2=17.78,P<0.001).Major depressive disorder,generalized anxiety disorder and non-specific depression prevalence were higher in female than in male(1.03%vs 0.59%,X2=4.20,P=0.04;0.53%vs 0.16%,X2=6.88,P=0.009;0.43%vs 0.13%,X2=5.75,P=0.016).Conclusions Mental disorders seriously affect the social and economic development of Guangzhou areas,patients with major depressive disorder or alcohol use disorder and schizophrenia are major target population for community mental health services.更多还原