【摘要】 目的探讨布-加综合征围手术期的危险因素。方法回顾性分析1995—2004年收治的布-加综合征确诊者中514例的临床资料。全组患者均行手术治疗。结果单因素分析发现年龄、合并症、吸烟、饮酒、腹水、黄疸、电解质紊乱、营养状况、术后低血压、术中出血、白蛋白、手术时间、手术时机、病理类型、血糖、出血史和凝血酶原时间(χ2=-5.089～234.858,P=0～0.028)等可能是布-加综合征围手术期的危险因素。多变量Logistic回归分析结果提示饮酒、病理类型、手术时间、术中失血、营养状况、术后低血压、黄疸、电解质紊乱、血糖和严重并发症(χ2=-0.912～2.147,P=0～0.07)等10指标为布-加综合征围手术期的独立危险因素。结论布-加综合征围手术期的高危因素能很好的反映布-加综合征患者围手术期的危险性,为手术时机的选择和指导预后有一定的临床参考价值。更多还原

【Abstract】 Objective To evaluate the peri-operative risk factors in patients with Budd-Chiari syndrome(B-CS).Methods Five hundred and forteen cases of B-CS with complete clinical data were analyzed retrospectively.All the patients underwent surgical procedures.Results The univariate analysis revealed that age,concomitant disease,smoking,drinking,ascites,jaundice,electrolyte disorder,nutrition,postoperative hypotension,operative blood loss,albumin level,operation time,operation timing,pathologic classification,level of blood sugar,history of hemorrhage and prothrombin time(χ2=-5.089~234.858,P=0~0.028) were possible perioperative risk factors of Budd-Chiari syndrome.The multivariate logistic regression analysis demonstrated that alcohol drinking,pathologic classification,operation time,operative blood loss,nutritional status,postoperative hypotension,jaundice,electrolyte disorder,level of blood sugar and severe complications(χ2=-0.912~2.147,P=0~0.07) were independent peri-operative risk factors of Budd-Chiari syndrome.Conclusions Peri-operative high risk factors of Budd-Chiari syndrome can reflect the risks of Budd-Chiari syndrome,and can be very valuable as clinical reference for selection of operation timing and evalution of prognosis.更多还原