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一株红曲霉菌种的诱变选育及其功能性产物测定

Mutagenesis screening of a Monascus strain and determination of its functional products

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【作者】 成剑峰王勇亮何于飞刘文静郭文娟胡红娟

【Author】 CHENG Jianfeng1,WANG Yongliang1,HE Yufei1,LIU Wenjing2,GUO Wenjuan1,HU Hongjuan1(1.Shanxi Food Industrial Research Institute,Taiyuan 030024,China;2.Shanxi Analysis and Testing Center,Taiyuan 030025,China)

【机构】 山西省食品工业研究所山西省分析测试中心

【摘要】 从我国传统糖化发酵剂中分离到产lovastatin的功能性红曲霉菌株,采用微波与离子束对该菌株进行了复合诱变选育工作,使其lovaststin的产量比照出发菌种提高了500%,培养条件优化后产量达到1.8mg/g,并对桔青霉素的含量进行了测定。

【Abstract】 A wide lovastatin-producing Monascus strain was isolated from Chinese traditional saccharifying starter which was widely used in food fermentation industry.A mutant of the Monascus strain was achieved by compound mutagenesis of microwave and ion-beam.The lovastatin yield of the mutant was raised to 500% compared with the wide Monascus strain.The lovastatin yield of the mutant was 1.8 mg/g after the optimization of fermentation conditions.The content of citrinin was also determined.

【关键词】 红曲霉lovastatin离子束微波桔青霉素
【Key words】 Monascuslovastatinion-beammicrowavecitrinin
  • 【分类号】Q93-3
  • 【被引频次】8
  • 【下载频次】217
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