【摘要】 在灵芝基础培养基中添加蛋白核小球藻粉,灵芝能对小球藻细胞进行生物破壁,同时进行生物转化。提取转化多糖,与基础培养基所产多糖进行比较,研究对荷瘤动物免疫功能的影响。结果表明,产生的转化多糖能显著提高荷瘤小鼠白细胞的数量、脾细胞增殖能力和单核巨噬细胞吞噬能力等免疫学功能功能,对其他免疫调节功能也有一定的提高作用,从而显著地提高了抑瘤效果。更多还原

【Abstract】 Ganoderma lucidum could break cell wall of Chlorella pyrenoidosa and produce bioconverted-polysaccharides when C.pyrenoidosa powder was appended in basic medium of G.lucidum.Effects on immunological function of tumor-beard mice were studied though comparing the polysaccharides from basic media with bioconverted-polysaccharides.The result showed the bioconverted polysaccharides could significantly increase the number of white blood cell,the proliferation of lymphocytes,and the phagocytic function by macrophages at the optimum dose.Therefore,the anti-tumor effect was enhanced significantly.更多还原