【摘要】 目的:观察益肺汤抗炎免疫与化痰镇咳作用。方法:二甲苯、醋酸诱发的急性渗出性炎症;氨水诱发咳嗽;酚红法测定化痰作用;溶血素测定血清抗体。结果:益肺汤高、低剂量组服药7d,对二甲苯诱发的急性炎性肿胀抑制率分别为10.9%、6.9%;对醋酸引起的小鼠腹腔毛细血管通透性抑制率分别为16.6%(P<0.05)、8.6%。对氨水引发的小鼠咳嗽潜伏期延长26.6%(P<0.05)、26.6%(P<0.05);咳嗽次数减少15.0%(P<0.05)、2.7%;气管分泌作用比对照组增加30.0%、21.8%;小鼠溶血素含量,比模型组提高52.0%(P<0.01)、44.1%(P<0.01);小鼠体重、白细胞、胸腺、脾脏分别比模型组提高16.0%、10.8%,55.8%(P<0.01)、71.2%(P<0.01),100.7%(P<0.01)、83.8%(P<0.01),26.3%(P<0.05)、47.7%(P<0.05)。结论:益肺汤有镇咳、化痰、抗炎、增加免疫力作用。更多还原

【Abstract】 Objectiv:To study the effect of yifei formula on anti-inflammatory and immunization,resolving phlegm and cough-remedy.Methods:dimethylbenzene and acetic acid inducing inflammatory,ammonia water inducing cough,phenol red excretion test(resolving phlegm),hemolysin test(antibody).Results:Compared with control group,cough latency of yifei formula treatment group was prolongated(P<0.05),cough counting decreased(P<0.05)by ammonia water inducing cough in mice.Antibody content of treatment group was increased(P<0.05)in immune-suppressive mice by prednisone acetate.Conclusion:yifei formula can effectively reform lung function,inhibite cough,prolongat cough latency,increase antibody content.更多还原