【摘要】 目的探讨2型糖尿病患者踝臂指数(ABI)和尿微量白蛋白(MAU)的联系。方法52例2型糖尿病患者分为非PAD组(ABI≥0.9)29例和PAD组(ABI<0.9)23例,分析两组的病程、糖化血红蛋白(HbA1C)、尿素氮(BUN)、肌酐(Scr)、尿微量白蛋白(MAU)等指标。结果PAD组的病程[(32.35±15.50)a]、收缩压[(154±1.08)mmHg]、HbA1[c(8.69±1.08)%]、MAU[(105.13±129.38)mg/L]、BUN[(6.53±1.12)mmol/L]、Sc[r(108.0±21.7)μmol/L]水平均高于非PAD组[(24.21±11.51)a、(140±21)mmHg、(8.03±1.20)%、(44.15±33.72)mg/L、(5.99±0.69)mmol/L、(96.2±18.1)μmol/L],差别有统计学意义(P<0.05);逐步回归分析显示,MAU和BUN是影响ABI的独立因素。结论ABI与MAU和BUN密切相关;伴有MAU的2型糖尿病患者更需要周围血管病变的检测。更多还原

【Abstract】 Objective To discuss the relationship between the ankle brachial index (ABI) and microalbuminuria (MAU) in patients with type 2 diabetes mellitus. Methods 52 patients with type 2 diabetes mellitus were divided into the PAD group (n=23, ABI<0.9)andtheun-PADgroup (n=29,ABI≥0.9).Thelevelsofcourseofdisease,HbA1C,BUN,ScrandMAUintwogroupsweremeasured. Results The levels of course of disease, systolic blood pressure, HbA1C, BUN, Scr and MAU in the PAD group were obviously higher than the un-PAD group (32.35 15.50 vs 24.21, 154 23 vs 140 21 8.69 1.08 vs 8.03 1.20, 105.13 129.38 vs 44.15 33.72, 6.53 1.12 vs 5.99 0.69, 108.0 21.7 vs 96.2 18.1 all P<0.05). The gradual regressive analysis indicated that MAU and BUN were independent factors which affected ABI. Conclusion The patients with type 2 diabetes mellitus and MAU should be more necessarily detected pathological changes in circumambient vessel.更多还原