【摘要】 目的通过随机分组对照,观察升黄益智颗粒对阿尔茨海默病(AD)患者的治疗效果。方法临床筛选AD患者,随机分为中药组(升黄益智颗粒)和西药组(多奈哌齐)。治疗前和90 d疗程结束后,分别采用精神状态速捡表(MMSE)评价患者的认知功能及痴呆严重程度,采用AD评定量表的认知次级量表(ADAS-cog)评价患者的认知功能及精神行为,所得量表积分进行组间和组内治疗前后比较。结果90 d疗程结束后,两组MMSE和ADAS-cog量表评分均较治疗前有明显改善(P<0.01),而两组间比较差异无统计学意义(P>0.05)。结论升黄益智颗粒能有效改善AD患者的痴呆症状。更多还原

【Abstract】 Objective To explore the protective effect of Shenghuangyizhi granule on patients with Alerzheimer′s disease(AD).Methods Patients with AD were selected and divided into Chinese traditional medicine group(Shenghuangyizhi granule) and western medicine(Donepezil).MMSE was used to value the patients′ cognitive function and the degree of dementia,the ADAS-cog was used to value the patients′ cognitive function and mental behavior before the treatment and after the treatment 90 days.Results The scores of MMSE and ADAS-cog assessment scale after treatment were all better than those before treatment in two groups and there was no difference between the treatment groups in the scores(P<0.01).Conclusions Shenghuangyizhi granule can improve the AD patients′ dementia symptom.更多还原