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低频重复经颅磁刺激对脑外伤患者认知功能的影响
Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation on Cognitive Function of Patients with Brain Injury
【摘要】 目的:观察重复性经颅磁刺激(rTms)改善脑外伤患者认知障碍的作用。方法:将60例脑损伤患者随机分为rTms组和对照组各30例,均按神经外科常规处理和治疗。rTms组加用低频rTms刺激双侧前额叶,30次为1个序列。治疗前后2组均进行精神状态量表(MMSE)、Rivermead行为记忆(RBMT)及符号划消测验评分。结果:治疗20 d后,2组MMSE及RBMT评分与治疗前比较均有明显提高(P<0.01或0.05);2组间差值比较,rTms组明显高于对照组(P<0.05)。符号划消测验评分rTms组的错划率与治疗前及对照组比较均明显降低(P<0.05),对照组治疗前后无明显改善。漏划率治疗前后2组均无明显变化。结论:低频rTms对促进脑外伤患者认知功能的恢复有更明显作用。
【Abstract】 Objective: To observe the roles of repetitive transcranial magnetic stimulation(rTMS) on cognitive disorder of patients with brain injury.Methods: Sixty patients with brain injury were divided into rTMS group and control group randomly,and received conventional therapy.In addition,the patients in rTMS group were subjected to low frequency rTMS treatment.Mini-Mental State Examination(MMSE),Rivermead Behavioral Memory Test(RBMT) and Cancellation Test were performed in the two groups before and after treatment.Results: Compared with those before the treatment,the MMSE and RBMT scores in two groups 20 days after the treatment were increased obviously(P<0.01 or 0.05).The scores in rTMS group were significantly higher than in control group(P<0.05).The cancellation test revealed that false rate in rTMS group was decreased as compared with that before treatment and in control group(P<0.05),but there was no significant improvement in false rate in control group,and there was no obvious change in clepsydra rate in the two groups before and after treatment.Conclusion: Low frequency rTMS could more significantly promote the recovery of cognitive function in patients with brain injury.
【Key words】 repetitive transcranial magnetic stimulation; brain injury; cognitive function;
- 【文献出处】 中国康复 ,Chinese Journal of Rehabilitation , 编辑部邮箱 ,2009年04期
- 【分类号】R651;R454
- 【被引频次】15
- 【下载频次】325