【摘要】 目的通过对新疆汉族和维吾尔族老年冠心病患者经皮冠状动脉介入治疗(PCI)时靶病变冠状动脉钙化检测及干预结果比较,探讨介入治疗中不同民族老年冠心病患者冠状动脉粥样硬化斑块钙化(CAC)检出率是否存在差异及其临床意义。方法回顾性分析我院2005年1月至2006年12月成功接受PCI的汉族和维吾尔族老年(年龄≥60岁)冠心病患者的冠状动脉造影结果,PCI并发症等临床资料。结果545例汉族和维吾尔族老年冠心病患者CAC总检出率为37.6%。其中维吾尔族患者CAC的检出率为49.3%,明显高于汉族患者29.8%(P<0.05),维吾尔族男性患者CAC的检出率明显高于汉族男性患者(55.3%比35.0%,P<0.05),而女性患者两组间差异无统计学意义(22.5%比19.2%,P>0.05)。维吾尔族患者术中冠状动脉夹层发生率明显高于汉族患者(37.8%比19.3%,P<0.05)。亚组分析,维吾尔族患者中91.8%冠状动脉夹层发生于靶血管病变CAC患者,略高于汉族患者(82.7%),但差异无统计学意义(P>0.05)。PCI术中慢血流发生率维吾尔族患者较汉族患者高(28.7%比9.3%,P<0.05);而支架内急性血栓发生率,两组间差异无统计学意义。结论新疆汉族和维吾尔族老年冠心病患者冠状动脉钙化发生率存在差异,致使维吾尔族患者PCI术中冠状动脉夹层和慢血流的发生率明显高于汉族患者。因此对维吾尔族患者应选择恰当的技术和方法减少术中冠状动脉夹层和慢血流的发生。更多还原

【Abstract】 Objective To compare the difference in incidence and therapeutic outcomes of coronary calcification between old Han and Uygur CHD patients in Xinjiang rovince after percutaneous coronary intervention.Methods We retrospectively analyzed the coronary angiography results and complications after PCI in the aged Han and Uygur CHD(age≥60) patients who had received PCI therapy from January 2005 to December 2006 in our hospital.Results Among 545 patients(Han 282,Uygur 263),the overall detection rate of coronary artery calcification was 37.6%,and the incidence of coronary calcification in the Uygur group was significantly higher than in the Han patients group(49.3% vs 29.8%,P<0.05).The incidence of coronary artery dissection during PCI procedure in the Uygur group was higher than in the Han group(37.8% vs 19.3%,P<0.05).The location of coronary artery dissection was often found in calcified vessel,but there were no difference between the two groups(91.8% vs 82.7%,P>0.05).There was higher rate of coronary slow flow in the Uygur group than in the Han group(28.7% vs 9.3%,P<0.05).There was no significant difference in the incidence of stent thrombosis between the 2 groups(P>0.05).Conclusion Coronary calcification can be found more often in old Uygur CHD patients compared with Han patients in Xinjiang.The incidence of coronary artery dissection and slow flow was higher in the Uygur patients than in Han patients.Special comcerns in avoiding coronary artery dissection and slow flow should be applied to Uygur patients.更多还原