【摘要】 目的了解临床分离的常见革兰阴性杆菌的分布及耐药情况,为临床合理用药提供依据。方法对2006年1-12月临床送检各类标本中培养分离的697株常见革兰阴性杆菌,采用WalkAway-40全自动细菌鉴定及药敏测试仪以及NC31鉴定板进行分析。结果最常见的革兰阴性菌株为铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌、鲍氏/溶血不动杆菌与嗜麦芽寡养单胞菌,其检出率分别为24.25%、23.67%、21.67%、11.33%、10.90%与8.18%,从总的耐药情况显示,革兰阴性杆菌(除嗜麦芽寡养单胞菌外)对亚胺培南耐药率最低。结论医院革兰阴性杆菌耐药严重,临床要定期进行细菌耐药监测,合理使用抗菌药物。更多还原

【Abstract】 OBJECTIVE To investigate the resistance and distribution of the Gram-negative bacilli and conduct clinical medication.METHODS A total of 697 strains of Gram-negative bacilli isolated from the all sorts of samples from Jan 2006 to Dec 2006 were analyzed by WalkAway-40 system with NC31 system.RESULTS The dominant strains were Pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumoniae,Enterobacter cloacae,Acinetobacter baumannii and Stenotrophomonas maltophili.The resistance rate of the main Gram-negative bacilli against imipenem was the lowest.CONCLUSIONS Most of Gram-negative bacilli in nosocomial infection are highly resistant to drugs.It is very important to use antibiotics reasonably against nosocomial infection.更多还原