【摘要】 目的探讨行损伤控制性剖腹术及腹腔填塞的患者术后感染情况及病原菌分布规律,分析术后感染的危险因素。方法回顾性分析2002年2月-2007年2月应用纱布填塞控制腹腔大出血患者术后的感染情况和细菌学资料。结果共26例患者常见的术后感染依次为肺炎(57.7%)、菌血症(50.0%)及尿路感染(15.4%),共检出病原菌244株,最常见的病原菌依次为铜绿假单胞菌(27.0%)、葡萄球菌属(15.6%)、鲍氏不动杆菌(13.9%)及克雷伯菌属(11.1%);未发现纱布培养阳性与术后感染(P=0.10)或死亡(P=1.00)显著相关;多因素回归分析提示术前腹腔感染(OR=22.4,P=0.02)和剖腹术次数增多(OR=3.69,P=0.05),是腹腔填塞患者术后新发感染的独立危险因素。结论行损伤控制性剖腹术及腹腔填塞的患者术后感染率较高,感染类型及致病菌分布符合ICU获得性感染特点,术前腹腔感染和剖腹术次数增多是腹腔填塞患者术后新发感染的独立危险因素。更多还原

【Abstract】 OBJECTIVE To determine the prevalence of post-operative infections in patients who underwent damage control laparotomy(DCL) with abdominal packing and to identify the risk factors,mortality and predominant pathogens.METHODS A retrospective study of postoperative infections and microbiology in patients who underwent abdominal packing as an adjunct of DCL to control coagulopathic hemorrhage over a 5 year period(Feb 2002-Feb 2007) were performed.RESULTS A total of 26 patients were studied.Pneumonia/lower respivatory tract infection was the prominant type of infection(57.7%),followed by bacteremia(50.0%),urinary tract infection(15.4%) and wound infection(15.4%).Of the 244 organisms isolated from various sites,the most frequently isolated bacteria were Pseudomonas aeruginosa(27.0%),Staphylococcus species(15.6%),Acinetobacter baumannii(13.9%),and Klebsiella species(11.1%).No statistical correlation was found between positive packs and postoperative infection(P=0.10) or death(P=1.00).Multivariate regression analysis revealed that pre-existing abdominal infection(OR=22.4,P=0.02) and increased number of surgical procedures(OR=3.69,P=0.05) were the independent risk factors for post-operative infections.CONCLUSIONS Patients who undergo DCL with packing have a high incidence of postoperative infections.Pathogens and distribution are same as acquired infections.Pre-existing abdominal infection and increased number of surgical procedures are the independent risk factors for postoperative infections in these patients.更多还原