【摘要】 综述了近年来对酮内酯类抗生素C-6位、C-9位、6,11-O-桥酮内酯、C-11,12位及C-13位等处结构修饰方面的新进展,重点介绍了化合物对金黄色葡萄球菌、肺炎链球菌等细菌的体外抗菌活性。更多还原

【Abstract】 This article reviewed the recent progress on the structural modification of the ketolide antibiotics at C-6,C-9,6,11-O-bridged ketolides,C-11,12 and C-13 position.The in vitro activities against S.aureus and S.pneumo were introduced.更多还原