【摘要】 目的探讨急性脑梗死患者血清超敏C-反应蛋白(hs-CRP)水平变化与脑梗死部位、严重程度及预后的关系。方法测定120例急性脑梗死患者和90名健康人血清hs-CRP的含量,按脑卒中患者临床神经功能缺损程度评分标准对患者进行评分,分组比较。结果脑梗死组血清CRP水平明显高于正常对照组(P<0.01)。不同部位梗死患者血清hs-CRP水平比较没有差异。脑梗死轻、中、重型患者血清hs-CRP水平差异有统计学显著性(P<0.05)。血清CRP水平越高的脑梗死患者病情越严重,临床预后差。结论血清hs-CRP水平增高与脑梗死的发生和严重程度有密切关系,而与病变部位无关。更多还原

【Abstract】 Objective To investigate the changes of the serum level of highly sensitive C-reactive protein (hs-CRP) in patients with acute cerebral infarction and its relationship to the lesions、 severity of cerebral infarction. Methods The serum level of hs-CRP in 120 patients and 90 healthy persons was determined. All the patients were scored by clinic neurological deficit scale ,and compared in groups. Results The serum level of hs-CRP in the patients was significantly higher than that in normal controls ( P < 0.01),between natiewtn with different lesion infarction-erum hs-CRP levels had no difference.it was significantly higher in the serious group than in the middle and mild groups ( P < 0.05 ). Conclusions The serum level of hs-CRP is closely correlated with the severity of cerebral infarction. Had nothing to do with the lesion localion.更多还原