【摘要】 目的:研究广西产夜香牛生物活性化学成分。方法:用鼠性肾上腺髓质嗜铬细胞瘤PC-12细胞活性跟踪筛选,柱色谱方法分离化合物,谱学方法鉴定化合物结构。结果:分离得到12个化合物,根据谱学数据分析鉴定其结构分别为(-)-clovane-2,9-diol(1),caryolane-1,9β-diol(2),洋芹素(3),金圣草素(4),木犀草素(5),金圣草素-7-O-β-D-葡萄糖苷(6),木犀草素-7-O-β-D-葡萄糖苷(7),槲皮素(8),洋芹素-4′-O-β-D-葡萄糖苷(9),金丝桃苷(10),β-amyrin aceate(11),lupeol acetate(12)。结论:化合物1,2,6和10均为首次自该属植物中分离得到。更多还原

【Abstract】 Objective: To study the constituents of the whole herbs of Vernonia cinerea by bio-activity guided isolation with PC-12 model.Method: The constituents were separated by column chromatography and the structures were elucidated by spectroscopic methods.Result: Ten compounds were identified to be(-)-clovane-2,9-diol(1),caryolane-1,9β-diol(2),apigenin(3),chrysoeriol(4),luteolin(5),thermopsoside(6),luteolin-7-O-β-D-glucoside(7),quercetin(8),apigenin-4′-O-β-D-glucoside(9),hyperin(10),β-amyrin aceate(11),lupeol acetate(12).Conclusion: Compounds 1,2,6 and 10 were isolated from this genus for the first time.更多还原