【摘要】 目的:研究糖尿病足截肢标本上动脉内终末糖基化产物(AGEs)的表达与糖尿病足中医辨证分型的相关性。方法:100例患者分为气血两虚瘀阻证、气阴两虚瘀阻证、脉络热毒证,对三型进行动脉AGEs的免疫组化研究。结果:在动脉中脉络热毒证表达最弱,气血两虚瘀阻证表达最强。各证型之间AGEs表达具有显著性差异(P<0.01)。结论:糖尿病足中医辨证分型与AGEs的表达具有较高的相关性。更多还原

【Abstract】 Objective To investigate the associativity between TCM syndrome differentiation and pattern types for diabetic foot and expression of advanced glycosylation endoproducts(AGEs) in arteries of amputation. Methods One hundred cases with diabetic foot were divided into stagnant deficiency of both Qi and blood type, stagnant deficiency of both Qi and Yin type and heat toxin in collaterals type according to syndrome differentiation in TCM. The studying of the expression of AGEs in artery was with immunohistochemistry method. Results The expression of AGEs was highest in stagnant deficiency of both Qi and blood type and lowest in heat toxin in collaterals type. There were significant differences for expression of AGEs among the three types(P<0.01). Conclusion There is high associativity between TCM syndrome differentiation and pattern types for diabetic foot and expression of AGEs.更多还原