【摘要】 目的总结1980至2008年国内外公开发表的以及我院建院以来诊治的子宫颈微偏腺癌(MDA)的临床及病理特点。方法分别以子宫颈微偏腺癌和子宫颈恶性腺瘤的中、英文作为检索词,检索1980至2008年国内外公开发表的文献,并结合我院诊治4例子宫颈MDA,进行meta分析。结果发病年龄为20～78岁,平均年龄44.66岁,中位数年龄43岁;临床表现以大量阴道排液或阴道不规则流血、接触性出血为主,约占报道病例的88.83%;病理检查见浸润子宫颈深部肌层的大量黏液腺体,腺体浸润深部血管及神经组织;治疗方式上以手术为主,术后辅助放、化疗;临床分期和手术方式在预后方面起着重要的作用。结论在临床上,应高度警惕子宫颈MDA,必要时行子宫颈锥切、免疫组织化学以及MRI检查,以便能够早期诊断,早期治疗,从而提高子宫颈MDA患者的生存率。更多还原

【Abstract】 Objective To summarize the clinical and pathological features of minimal deviation adenocarcinoma(MDA)of cervix in the published articles during 1980-2008 and the cases diagnosed and treated in our hospital since 1883. Methods With minimal deviation adenocarcinoma of cervix or malignant adenoma of cervix as key words,we retrieved the published articles of MDA of cervix during 1980- 2008. A meta-analysis was carried out together with the 4 cases of our hospital. Results The age of onset was 20~78 years,and the average age was 44.66 years,median age was 43. 88.83% of the cases showed the clinical manifestation of massive vaginal apocenosis or irregular vaginal bleeding,bleeding after contact. Massive mucus glands infiltrating deep tunicae muscularis of cervix were seen in pathological examination. Glands infiltrated deep blood vessles and nervous tissue. The treatment method was mainly operation assisted with post-op radiotherapy and chemotherapy. Clinical stage and operation method were very important for the prognosis. Conclusion In clinical,we should pay enough attention to MDA of cercix. If necessary,cervical conization,immunohistochemistry and MRI should be taken in order to early diagnose and treat and thus elevate the survival rate of MDA of cervix patients.更多还原