【摘要】 目的:研究腹部手术后使用精氨酸强化的全肠外营养(TPN)对患者营养及免疫状况的影响。方法:选择67例接受腹部手术和TPN的患者,随机分为对照组(常规TPN支持,24例)、试验Ⅰ组(TPN+15g精氨酸,25例)和试验Ⅱ组(TPN+30g精氨酸,18例),术后连续应用3d。结果:精氨酸强化的TPN提高了术后氮平衡的水平,促进血浆白蛋白、总蛋白的恢复,并使CD4+、CD4+/CD8+升高。在观察的周期内对免疫球蛋白和补体C3、C4的影响没有显著性意义。结论:精氨酸强化的TPN能提高术后患者的营养和免疫指标,提高TPN支持的效果。更多还原

【Abstract】 OBJECTIVE:To evaluate the effects of arginine-enriched total parenteral nutrition(TPN)on the nutritional and immune parameters of patients undergoing abdominal surgery.METHODS:67 patients undergoing abdominal surgery were randomly assigned to receive routine TPN(control group,n=24),TPN plus 15 g arginine(n=25,trial group Ⅰ)or TPN plus 30 g arginine(n=18,trial group Ⅱ)for 3 days postoperatively.RESULTS:Arginene-enriched TPN significantly improved postoperative nitrogen balance,promoted the recovery of plasma-albumin and total protein,and elevated the levels of CD4+ and CD4+/CD8+,but no significant difference was noted for immunoglobulin,complement C3 and complement C4 during trial period.CONCLUSION:Arginene-enriched TPN can improve patients’ postoperative nutritional and immune parameters and enhance the efficacy of TPN support.更多还原